Calorie restriction and longer life in nematode worms

A paper just published in PLoS Genetics has found that diet restriction suspends development in nematode worms, and doubles their lifespan. The study found that C. elegans could be starved for at least two weeks and still develop normally once feeding resumed. Because the meter isn’t running while the worm is in its arrested state, this starvation essentially doubles the two-week lifespan of the worm. This may suggest a similar mechanism is operating in primates (and humans?) on calorie-restricted diets.

http://www.plosgenetics.org/article/info%3Adoi%2F10.1371%2Fjournal.pgen.1004426

Over the last 80 years, researchers have put a menagerie of model organisms on a diet, and they’ve seen that nutrient deprivation can extend the lifespan of rats, mice, yeast, flies, spiders, fish, monkeys and worms anywhere from 30 percent to 200 percent longer than their free-fed counterparts.

Of course, if your extended life span is spent obsessing about counting calories, and thinking about it, and telling your friends obsessively about it, others may not think the extra years are a benefit.

Advertisements
This entry was posted in Uncategorized. Bookmark the permalink.

Leave a Reply

Fill in your details below or click an icon to log in:

WordPress.com Logo

You are commenting using your WordPress.com account. Log Out / Change )

Twitter picture

You are commenting using your Twitter account. Log Out / Change )

Facebook photo

You are commenting using your Facebook account. Log Out / Change )

Google+ photo

You are commenting using your Google+ account. Log Out / Change )

Connecting to %s